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Intrinsic Responses

The molecular mechanisms by which early experiences “get under the skin”

Researchers in this theme explore how, when, and under what circumstances early life social and environmental factors become “biologically embedded” to affect neural, endocrine, and immune systems at the molecular level. Research projects in this theme investigate the role of hormonal signaling pathways, as well as the metabolome, proteome, inflammasome, microbiome, and epigenome, in mediating the effects of the social environment on child health and development.